Figure 2.
Efficient inhibition of Int6/eIF3e expression with siRNA. (A) qRT-PCR data showing strong Int6 mRNA depletion in GBM cells transfected with Int6 specific siRNA (siInt6) compared to control cells transfected with a scrambled sequence (siScr) (*** p < 0.001 siInt6 versus siScr, n > 4); (B) Western blots showing efficient inhibition of Int6/eIF3e protein expression in LN18, SF767, U87 and U251 GBM cells transfected with Int6 specific siRNA (siInt6) (n = 10).