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. 2014 Jan 29;15(2):2172–2190. doi: 10.3390/ijms15022172

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© 2014 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 2. — Efficient inhibition of Int6/eIF3e expression with siRNA. (A) qRT-PCR data showing strong Int6 mRNA depletion in GBM cells transfected with Int6 specific siRNA (siInt6) compared to control cells transfected with a scrambled sequence (siScr) (*** p < 0.001 siInt6 versus siScr, n > 4); (B) Western blots showing efficient inhibition of Int6/eIF3e protein expression in LN18, SF767, U87 and U251 GBM cells transfected with Int6 specific siRNA (siInt6) (n = 10).