Histological analysis of colon of different groups of animals with TNBS-induced colitis. (A) untreated animals: positive control; (B) a negative control; (C,D) treated every 12 and 24 h, respectively, with 25 mg/kg of glucans of Caripia montagnei; (E,F) treated at intervals of 12 and 24 h, respectively, with 50 mg/kg glucans of C. montagnei; (G,H) treated every 12 and 24 h, respectively, with 75 mg/kg of glucans of C. montagnei; (I,J) treated every 12 and 24 h, respectively, with 100 mg/kg of dexamethasone. The figures with arrows indicate destruction of the mucosal layer with infiltration of inflammatory cells.