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. 2014 Feb 17;15(2):2712–2721. doi: 10.3390/ijms15022712

Table 3.

Stratified analyses between ETS1 rs1128334 G/A and WDFY4 rs7097397 A/G polymorphisms and risk of rheumatoid arthritis.

Variable ETS1 rs1128334 G/A (Case/Control) OR (95% CI) WDFY4 rs7097397 A/G (Case/Control) OR (95% CI)

GG GA AA GG GA AA AA AG GG AA AG GG
Gender

Male 33/99 37/75 8/20 1.00 1.48 (0.85–2.58); p:0.168 1.20 (0.48–2.98); p:0.695 33/87 39/88 9/22 1.00 1.17 (0.67–2.03); p:0.579 1.08 (0.45–2.58); p:0.865
Female 102/192 105/223 34/64 1.00 0.89 (0.64–1.24); p:0.479 1.00 (0.62–1.62); p:1.000 89/237 121/197 30/60 1.00 1.64 (1.17–2.28); p:0.0037 1.33 (0.81–2.20); p:0.263

Age

<55 69/143 68/156 23/34 1.00 0.90 (0.60–1.35); p:0.623 1.40 (0.77–2.56); p:0.271 55/176 79/130 26/34 1.00 1.95 (1.29–2.94); p:0.0016, pcorrect:0.0032 2.45 (1.35–4.43); p:0.0031, pcorrect:0.0062
≥55 66/148 74/142 19/50 1.00 1.17 (0.78–1.75); p:0.450 0.85 (0.47–1.56); p:0.603 67/148 81/155 13/48 1.00 1.15 (0.78–1.71); p:0.476 0.60 (0.30–1.18); p:0.137

CRP status

Positive 67/291 72/298 20/84 1.00 1.05 (0.73–1.52); p:0.799 1.03 (0.59–1.80); p:0.906 65/324 82/285 13/82 1.00 1.43 (1.00–2.06); p:0.051 0.79 (0.42–1.50); p:0.473
Negative 68/291 70/298 22/84 1.00 1.01 (0.69–1.46); p:0.978 1.12 (0.65–1.92); p:0.678 57/324 78/285 26/82 1.00 1.56(1.07–2.27); p:0.0216
pcorrect:0.0432
1.80 (1.07–3.04); p:0.0273
pcorrect:0.0546

ACPA status

Positive 66/291 76/298 17/84 1.00 1.12 (0.78–1.62); p:0.531 0.89 (0.50–1.60); p:0.703 61/324 80/285 19/82 1.00 1.49 (1.03–2.16); p:0.0340
pcorrect:0.0680
1.23 (0.70–2.17); p:0.475
Negative 69/291 66/298 25/84 1.00 0.93 (0.64–1.36); p:0.721 1.26 (0.75–2.11); p:0.390 61/324 80/285 20/82 1.00 1.49 (1.03–2.16); p:0.0340
pcorrect:0.0680
1.30 (0.74–2.27); p:0.365

The genotyping was successful in: 319 cases and 673 controls for ETS1 rs1128334 G/A; 321 cases and 691 controls for WDFY4 rs7097397 A/G; Bonferroni correction was performed to correct the p value (pcorrect).