Table 1. Transmission frequencies of NPC1;NPC2 genotypes from double heterozygote [Npc1+/–/Npc2+/–] matings.
| Number of animals per genotype (% found:% expected)
|
|||
|---|---|---|---|
| NPC2-/- | NPC2+/- | NPC2+/+ | |
| NPC1-/- | 30 (2.8:6.25) | 117 (11.1:12.5) | 49 (4.7:6.25) |
| NPC1+/- | 130 (12.3:12.5) | 260 (24.7:25.0) | 117 (11.1:12.5) |
| NPC1+/+ | 96 (9.1:6.25) | 155 (14.7:12.5) | 99 (9.4:6.25) |