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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Bioorg Med Chem. 2013 Dec 4;22(1):116–125. doi: 10.1016/j.bmc.2013.11.046

Figure 2.

Figure 2

General structures of PatA derivatives 2 and 3a–g. For first generation PatA analogs see Table 1 for modifications at R1, R2 and R. The fourth site of derivatization was level of unsaturation at C19–C20.