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. Author manuscript; available in PMC: 2015 Feb 21.
Published in final edited form as: Chem Soc Rev. 2014 Feb 21;43(4):1172–1188. doi: 10.1039/c3cs60311c

Figure-5.

Figure-5

Single-molecule (SM) study of amyloidogenesis for Sup35-NM: (A-C) SM anisotropy measurements revealed progressive conversion of the monomeric protein to the matured oligomers through intermediate oligomeric species. (D) Proposed amyloid pathway for the Sup35-NM. The figure is adapted from Krishnan et al., Proc. Natl. Acad. Sci., USA, (2012) 109:11172 105.