Table 4.

RRs of death from all causes by combinations of coffee consumption (including decaffeinated coffee) and caffeine intake.

	Quintiles of caffeine intake
	Q1-Q2	Q3	Q4-Q5
Men
Total coffee, <1/mo to 4/wk, cups
Median caffeine intake (mg/d)	33	164	338
Person-yr	175,021	28,477	11,715
No. of deaths	1602	237	99
Multivariable	1.0	0.97 (0.83-1.12)	0.91 (0.73-1.13)
Total coffee, 5 to 7/wk, cups
Median caffeine intake (mg/d)	71	179	307
Person-yr	71,136	85,037	54,586
No. of deaths	923	959	596
Multivariable	1.00 (0.91-1.10)	0.96 (0.88-1.06)	1.00 (0.90-1.12)
Total coffee, ≥2/day, cups
Median caffeine intake (mg/d)	46	192	451
Person-yr	33,971	26,837	214,186
No. of deaths	351	316	1805
Multivariable	0.92 (0.80-1.05)	1.09 (0.94-1.25)	0.91 (0.84-0.98)
Women*
Total coffee, <1/mo to 4/wk, cups
Median caffeine intake (mg/d)	98	302	511
Person-yr	313,837	62,955	143,116
No. of deaths	2022	415	962
Multivariable	1.0	0.90 (0.81-1.00)	0.79 (0.73-0.86)
Total coffee, 5 to 7/wk, cups
Median caffeine intake (mg/d)	161	292	397
Person-yr	234,597	126,844	41,575
No. of deaths	1570	859	314
Multivariable	0.98 (0.92-1.05)	1.01 (0.93-1.10)	1.04 (0.92-1.17)
Total coffee, ≥2/day, cups
Median caffeine intake (mg/d)	175	314	506
Person-yr	83,305	126,042	446,278
No. of deaths	456	662	2481
Multivariable	0.84 (0.76-0.93)	0.80 (0.73-0.88)	0.84 (0.78-0.89)

^*Follow-up since 1984. The person-years and cases are different for women from previous tables because of the different years of follow-up. Models included the same covariates as in Table 2. Values are relative risks and 95% confidence intervals.