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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Genet Epidemiol. 2013 Nov 15;38(1):1–9. doi: 10.1002/gepi.21776

Table I.

Type I error of famSKAT and famWS: in the sequence data (for two proportions of dense markers individuals, d =20% and d =100%) and in the imputation data (using best-guess genotypes and allelic dosages).

LowLD MedLD HighLD
α famSKAT famWS famSKAT famWS famSKAT famWS
Sequence data
d =20% 10−3 0.0007 0.0010 0.0006 0.0010 0.0006 0.0012
10−4 0.00002 0.00012 0.00004 0.00012 0.00002 0.00009
d =100% 10−3 0.0010 0.0011 0.0010 0.0011 0.0008 0.0011
10−4 0.00010 0.00012 0.00013 0.00006 0.00012 0.00012
Imputation data$
Best-guess
genotypes		 10−3 0.0010 0.0012 0.0010 0.0010 0.0009 0.0010
10−4 0.00007 0.00011 0.00008 0.00011 0.00010 0.00015
Allelic dosages 10−3 0.0010 0.0012 0.0009 0.0011 0.0009 0.0010
10−4 0.00012 0.00013 0.00007 0.00013 0.00011 0.00010
$

Imputation based on the previous d =20% of dense marker individuals