Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Nausea and vomiting (composite)
RCT 3-armed trial	68 women, mean gestational age ranged from 9.5–10 weeks	Intensity of change of Mean Rhodes Index baseline and over 4 days of treatment with metoclopramide 3 times daily for 5 days with placebo 3 times daily for 5 days	P = 0.025 Method of randomisation unclear		metoclopramide