Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Nausea
RCT Crossover design	40 women admitted to hospital with vomiting (all women were vomiting on the day of randomisation); gestational age range 6–16 weeks	Time to resolution of nausea with PC6 acupuncture (applied 5 mm beneath the skin on the lateral side of the forearm) with sham acupuncture (applied 1–2 mm beneath the skin on the lateral side of the forearm)	P = 0.032 VAS estimate for nausea different between groups at baseline (P = 0.009). Hence, only speed of resolution calculated Post crossover result Results presented graphically	Effect size not calculated	PC6 acupuncture
Vomiting
RCT Crossover design	40 women admitted to hospital with vomiting (all women were vomiting on the day of randomisation); gestational age range 6–16 weeks	Proportion of women who vomited day 4 7/17 (41%) with PC6 acupuncture (applied 5 mm beneath the skin on the lateral side of the forearm) 12/16 (75%) with sham acupuncture (applied 1–2 mm beneath the skin on the lateral side of the forearm)	P = 0.049 Result of borderline significance 7/40 (17%) not included in analysis	Effect size not calculated	PC6 acupuncture