Fig. 2.

DC cross-present a viral epitope from CD4⁺ primary lymphocytes infected with a WT HIV isolate. DC were cultured with irradiated CD4⁺ T cell blasts infected with different amounts of a primary HIV isolate in the presence or absence of LPS and tested by using an anti-Nef_73–82 CD8⁺ line as in Fig. 1. This experiment was carried out in the presence of AZT.