Table 1. WNT expression in myelomas and normal B lineage cells.
WNT
|
||||
---|---|---|---|---|
Cell type | 3a | 5a | 10b | 16 |
Naïve B cells | — | — | — | — |
GC B cells | — | — | — | — |
Memory B cells | — | — | — | — |
Plasma cells | — | — | — | — |
Total B cells | — | — | — | — |
Fibroblast | — | + | + | + |
BM stromal cells | — | + | + | — |
MM cell lines | 0/8 | 4/8 | 8/8 | 1/8 |
Purified primary MMs | 0/4 | 4/4 | 3/4 | 1/4 |
WNT expression was determined by RT-PCR as described in Materials and Methods. —, negative; +, positive. Numbers indicate no. positive/no. tested.