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. 2004 Apr 12;101(16):6164–6169. doi: 10.1073/pnas.0401471101

Table 1. Frequency of pre-B and B cell tumors induced by the Eμ-Myc transgene.

Pre-B lymphoma*
B lymphoma*
Genotype Frequency, % Incidence at 11 wk, % Frequency, % Incidence at 11 wk, %
Bim+/+ 6 of 18 (33) 11 12 of 18 (66) 0
Bim+/— 9 of 39 (23) 10 30 of 39 (77) 22
Bim—/— 3 of 11 (27) 34 9 of 11 (73) 57
*

Lymphomas were typed by flow cytometry of surface immunofluorescence: pre-B lymphoma (B220+ CD19+ IgM); and B lymphoma (B220+ CD19+ IgM+)

Cumulative incidence at 11 wk of age. The other tumor type was censored, so the incidence shown is independent of the competing risk of the other type

The frequency of B lymphoma in Bim+/— versus Bim+/+ Eμ-Myc mice was not significantly different (P = 0.41)