Table 2. Frequency of p19Arf alterations in Eμ-Myc lymphomas.

	P19Arf overexpressed		p19Arf undetectable
Genotype	Frequency, %	χ2; P*	Frequency, %	χ2; P*
Bim+/+	5 of 16 (31)		3 of 16 (19)
Bim+/-	1 of 21 (5)	4.7; 0.03	3 of 21 (14)	0.1; 0.71
Bim-/-	0 of 12 (0)	4.6; 0.03	0 of 12 (0)	2.5; 0.11

Lymphomas were assayed by immunoblotting for expression of p19Arf (see representative blot in Fig. 4).

^*Significance was determined by log-rank test in comparison with values for Eμ-Myc Bim^+/+ mice