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| P19Arf overexpressed
|
p19Arf undetectable
|
|||
|---|---|---|---|---|
| Genotype | Frequency, % | χ2; P* | Frequency, % | χ2; P* |
| Bim+/+ | 5 of 16 (31) | 3 of 16 (19) | ||
| Bim+/- | 1 of 21 (5) | 4.7; 0.03 | 3 of 21 (14) | 0.1; 0.71 |
| Bim-/- | 0 of 12 (0) | 4.6; 0.03 | 0 of 12 (0) | 2.5; 0.11 |
Lymphomas were assayed by immunoblotting for expression of p19Arf (see representative blot in Fig. 4).
Significance was determined by log-rank test in comparison with values for Eμ-Myc Bim+/+ mice
