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. 2014 Jan 31;155(4):1489–1497. doi: 10.1210/en.2013-1977

Figure 3.

Figure 3.

Y FISH/immunoflourescent images of the ectopic lesions and the uterus Y chromosome (red), CD45 (green), nuclei (blue). Panel A (CE) and panel B (CE/BZA) show Y chromosome signals in the ectopic lesions demonstrating engraftment of male bone marrow-derived stem cells. C, An example of a Y +/CD45+ leukocyte that was excluded from the analysis. Note the significantly lower number of Y chromosome signals recruited to the ectopic lesions under the influence of BZA, P < .0001. Panel D compares the number of Y+/CD45− cells recruited to the uteri (endometrial glands and stroma) in each treatment group. *, P = .04; **, P = .0006 The presence of endometriois results in reduced uterine stem cell engraftment whereas treatment restores stem cell engraftment to control levels. endo, endometriotic.