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RAD140 induces tissue-specific androgenic effects. Data show mean (± SEM) tissue weights of (A) seminal vesicles, (B) prostate, and (C) levator ani muscle from male rats in sham-GDX (open bar), GDX (solid bar), GDX+T (gray bar), and GDX+RAD140 (gray bar) conditions. D, Relative mRNA levels of ERα in the hypothalamus were determined across groups by real-time PCR. Data show expression relative to the Sham condition. *, P < .001 vs sham; Ψ, P < .0001 vs T; n ≥ 7 per condition.
