Table 1.
Study drugs by drug class, showing defined daily doses (DDDs) and proportion of patients (n=34 727) who received a prescription for each of these during the observation period
| Drug class and type | DDDs (mg) | No (% using drug) |
|---|---|---|
| Benzodiazepines: | ||
| Alprazolam | 1 | 19 ( 0.05) |
| Chlordiazepoxide | 30 | 1788 (5.15) |
| Clobazam | 20 | 164 (0.47) |
| Clonazepam | 8 | 802 (2.31) |
| Diazepam | 10 | 16 638 (47.91) |
| Flunitrazepam | 1 | 3 (0.01) |
| Flurazepam hydrochloride | 30 | 17 (0.05) |
| Loprazolam mesilate | 1 | 161 (0.46) |
| Lorazepam | 2.5 | 1472 (4.24) |
| Lormetazepam | 1 | 665 (1.91) |
| Midazolam (including all salts) | 15 | 523 (1.51) |
| Nitrazepam | 5 | 1557 (4.48) |
| Oxazepam | 50 | 597 (1.72) |
| Temazepam | 20 | 12 208 (35.15) |
| Triazolam | 0.25 | 0 (0) |
| Any benzodiazepine | — | 26 347 (75.87) |
| Z drugs: | ||
| Zaleplon | 10 | 481 (1.39) |
| Zolpidem tartrate | 10 | 2737 (7.88) |
| Zopiclone | 7.5 | 11 764 (33.88) |
| Any Z drug | — | 13 443 (38.71) |
| Other drugs: | ||
| Alimemazine tartrate | 30 | 331 (0.95) |
| Buspirone hydrochloride | 30 | 916 (2.64) |
| Chloral hydrate | 1000 | 72 (0.21) |
| Clomethiazole | 1500 | 400 (1.15) |
| Clomethiazole edisilate | 1500 | 82 (0.24) |
| Cloral betaine | 1000 | 472 (1.36) |
| Dichloralphenazone | 1300 | 0 (0) |
| Diphenhydramine hydrochloride | 200 | 0 (0) |
| Hydroxyzine hydrochloride | 75 | 2475 (7.13) |
| Melatonin | 2 | 66 (0.19) |
| Meprobamate | 1200 | 12 (0.03) |
| Methyprylone | 200 | 0 (0) |
| Promethazine hydrochloride | 25 | 1184 (3.41) |
| Sodium oxybate | 7500 | 0 (0) |
| Triclofos sodium | 1000 | 6 (0.02) |
| Any other drug | — | 7445 (21.44) |