Effects of VSV infection on body temperature during baseline (Base, open bar) and PI days 0, 1, 3, 5, 7, 10 and 14 (shaded bars). Values (mean ± SEM) are plotted for 12-h light and dark periods. (A) Direct strain comparison of VSV-induced changes in temperature between BALB/c and B6 mice. Data from each animal were normalized by subtracting baseline values from post-VSV infection values and averaged for strains. Baseline value (C°): BALB/c: 36.1 ± 0.05 (light period), 36.9 ± 0.07 (dark period), B6: 36.2 ± 0.09 (light period), 37.3 ± 0.09 (dark period). (B) Body temperature of B6 mice. (C) Body temperature of BALB/c mice. * denotes p < 0.05 relative to the baseline values at the comparable time point. # denotes significant differences between strains (p < 0.05).