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Membrane-associated NR2 protein complexes 24 hr after last training session in naïve, CR-trained, and PR-trained animals. ERK1/2, NR2A, and NR2B were expressed on the membrane and found in complexes. ERK1/2 interacted with NR2A and NR2B regardless of training, and association appeared greater with NR2A after PR. pERK1/2 were not found in complex with NR2 subunits, save for pERK2 bound to NR2B in the naïve state.
