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The frequency of TUNEL-Positive Nuclei in normal juvenile chondrocyte macroaggregate pellet cultures.
| Group | Control | rhTNF-α | AG-490 | rhTNF-α + AG-490 | MSU | MSU + AG-490 |
|---|---|---|---|---|---|---|
| Total Cells | 489 | 522 | 523 | 491 | 548 | 555 |
| TUNEL +ve (%) | 166 | 492 | 463 | 443 | 500 | 530 |
| TUNEL +ve (%) | 33.9 | 94.3 | 88.5 | 90.2 | 91.2 | 95.4 |
| Δ (%) | — | +178% | +161% | +166% | +169% | +181% |
TUNEL positive (TUNEL +ve) chondrocytes were enumerated from computer-assisted enhanced images
