Table 1.
DEPs in the LTA and AAL fractions.
| DEPs unique to LTA fractions | DEPs unique to AAL fractions | DEPs common to both LTA and AAL fractions |
|---|---|---|
| Actin, cytoplasmic 1nl | Alpha-2-macroglobulinha (CF, F) | C4b-binding protein alpha chainla (F) |
| Afamin bla (CF, F) | Apolipoprotein A-Iha (F) | Complement C3ha (F) |
| Alpha-1-antichymotrypsinha (F) | Apolipoprotein A-IIha (F) | Complement C5nl (F) |
| Alpha-1-antitrypsinha (CF, F) | Apolipoprotein A-IV*, ha | Fibronectin bla (F) |
| Angiotensinogen bla (F) | Apolipoprotein B-100 ha (F) | Inter-alpha-trypsin inhibitor heavy chain H4ma (F) |
| Apolipoprotein C-IIIma (F) | Apolipoprotein C-IIbla (F) | Thrombospondin-1la (F) |
| Apolipoprotein D ma (CF, F) | Apolipoprotein E bla (F) | |
| C4b-binding protein beta chain la (F) | Ceruloplasmin ha (CF, F) | |
| CD5 antigen-like*, bla | Complement component C6 bla (F) | |
| Coagulation factor Vbla | Haptoglobinha (CF) | |
| Coagulation factor XIII B chainbla | Hornerinla,* | |
| Complement component C7bla (CF, F) | Hyaluronan-binding protein 2bla | |
| Complement factor H bla (CF, F) | Ig lambda-2 chain C regionsunk,* | |
| Desmoplakinla,* | Inter-alpha-trypsin inhibitor heavy chain H2 ha (F) | |
| EGF-containing fibulin-like extracellular matrix protein 1la | Latent-transforming growth factor beta-binding protein 1la | |
| Extracellular matrix protein 1la (CF, F) | Protein disulfide-isomerasela,* | |
| Extracellular superoxide dismutase [Cu-Zn] la | Prothrombinla (CF, F) | |
| Fibrillin-1la | Serotransferrinha (CF, F) | |
| Fibrinogen alpha chainha (F) | Serum albumin*,ha | |
| Fibulin-1la | SPARC-like protein 1la | |
| Haptoglobin-related proteinnl (F) | Vimentinbla | |
| Ig mu chain C region bla (CF, F) | Vitronectinla (CF, F) | |
| Inter-alpha-trypsin inhibitor heavy chain H1ma (CF, F) | von Willebrand factorla (CF) | |
| Nucleobindin-1 la,* | ||
| Papilinnl | ||
| Phosphatidylinositol-glycan-specific phospholipase D bla | ||
| Pregnancy zone protein bla | ||
| Serum paraoxonase/arylesterase 1nl (F) | ||
| Transthyretinha (F) |
Low abundance (few ng/mL to < 2 μg/mL level);
borderline between low and medium abundance proteins (2 μg/mL to < 0.1 mg/mL);
medium abundance (0.1 mg/mL to < 0.2 mg/mL);
high abundance (0.2 mg/mL to > 1 mg/mL).
not listed. The scale for protein abundance used here is arbitrary and is simply introduced to facilitate the comparison and discussion.
core fucosylated;
fucosylated;
nonglycoprotein. The protein concentration used are from published or predicted values from Ref. [23]. Data on fucosylation are from Refs. [4, 12, 13, 26, 27] based on glycan analysis and/or the reactivity of the proteins with fucose specific lectins. All other glycoproteins listed in the table may be fucosylated but their fucosylation have not been reported yet in the literature.