Table 5.
Unadjusted and Adjusted Within Pair Association of CVHI (Per 5 Unit Change in Overall Score) With CIMT (in mm)
| Models | MZ+DZ Pairs (n=394) | MZ Pairs (n=242) | DZ Pairs (n=152) | |||
|---|---|---|---|---|---|---|
| Coefficient (Mean CIMT Difference in mm Per 5 Unit Change in Score) | P Value | Coefficient (Mean CIMT Difference in mm Per 5 Unit Change in Score) | P Value | Coefficient (Mean CIMT Difference in mm Per 5 Unit Change in Score | P Value | |
| Model‐1 (unadjusted) | −0.045 | <0.001 | −0.05 | <0.001 | −0.03 | 0.18 |
| Model‐2 (adjusted for age, college education, employment) | −0.04 | <0.001 | −0.05 | <0.001 | −0.025 | 0.26 |
| Model‐3 (further adjusted for depression, medications*) | −0.04 | <0.001 | −0.05 | <0.001 | −0.04 | 0.11 |
CIMT indicates carotid intima‐media thickness; CVHI, cardiovascular health index; DZ, dizygotic; MZ, monozygotic.
*
Medications include beta‐blockers, aspirin, angiotensin‐converting enzyme inhibitors, diabetes medication, and statins.