Table 4.
Prognostic Value of ECG Findings in Chagas Disease Elderly Patients (n=557) for Mortality, The Bambuí Cohort Study, 1997–2007
| ECG Variables | HR (95% CI) | |||
|---|---|---|---|---|
| Unadjusted | Adjusted for Age and Gender | Adjusted for Clinical Variables* | Fully Adjusted Model* | |
| Rhythm | ||||
| Sinus rhythm | 0.36 (0.28 to 0.47) | 0.42 (0.33 to 0.54) | 0.44 (0.34 to 0.56) | 0.44 (0.34 to 0.56) |
| Sinus tachycardia | 1.56 (0.69 to 3.50) | 1.36 (0.61 to 3.07) | 1.45 (0.64 to 3.27) | 1.52 (0.67 to 3.44) |
| Sinus bradycardia | 1.24 (0.72 to 2.13) | 1.22 (0.71 to 2.10) | 1.10 (0.63 to 1.94) | 1.10 (0.63 to 1.94) |
| Frequent VPB | 1.92 (1.36 to 2.72) | 2.16 (1.53 to 3.06) | 2.15 (1.51 to 3.06) | 2.15 (1.51 to 3.06) |
| Frequent SPB | 2.24 (1.60 to 3.13) | 1.66 (1.18 to 2.38) | 1.64 (1.15 to 2.32) | 1.57 (1.10 to 2.24) |
| Atrial fibrillation or flutter | 2.84 (1.91 to 4.21) | 2.35 (1.57 to 3.50) | 2.38 (1.54 to 3.68) | 2.35 (1.53 to 3.62) |
| Intraventricular block | ||||
| LBBB | 1.60 (0.88 to 2.93) | 1.24 (0.68 to 2.28) | 1.11 (0.60 to 2.06) | 1.08 (0.58 to 2.00) |
| RBBB | 1.55 (1.18 to 2.03) | 1.52 (1.16 to 2.00) | 1.48 (1.12 to 1.96) | 1.48 (1.12 to 1.96) |
| LAH+RBBB | 1.40 (0.95 to 2.06) | 1.34 (0.91 to 1.98) | 1.34 (0.90 to 1.99) | 1.36 (0.91 to 2.02) |
| LAH | 1.32 (0.87 to 2.02) | 1.16 (0.76 to 1.76) | 1.18 (0.77 to 1.81) | 1.38 (0.89 to 2.13) |
| Incomplete LBBB | 1.28 (0.73 to 2.24) | 1.55 (0.89 to 2.72) | 1.44 (0.81 to 2.55) | 1.49 (0.84 to 2.63) |
| Incomplete RBBB | 1.16 (0.70 to 1.93) | 1.20 (0.72 to 1.99) | 1.23 (0.74 to 2.05) | 1.25 (0.75 to 2.09) |
| Atrioventricular block | ||||
| First degree | 1.36 (0.87 to 2.13) | 1.20 (0.77 to 1.88) | 1.10 (0.70 to 1.74) | 1.01 (0.63 to 1.62) |
| Third degree or pacemaker | 1.66 (0.74 to 3.74) | 1.52 (0.67 to 3.42) | 1.07 (0.46 to 2.47) | 0.97 (0.42 to 2.26) |
| Ischemic | ||||
| Old MI and possible old MI | 2.21 (1.44 to 3.40) | 1.83 (1.23 to 2.90) | 1.84 (1.19 to 2.85) | 1.88 (1.22 to 2.91) |
| Major isolated ST‐T abnormalities | 1.27 (0.88 to 1.84) | 1.40 (0.96 to 2.03) | 1.50 (1.03 to 2.19) | 1.38 (0.94 to 2.03) |
| Minor isolated ST‐T abnormalities | 0.86 (0.67 to 1.10) | 0.81 (0.62 to 1.04) | 0.83 (0.64 to 1.08) | 0.80 (0.62 to 1.04) |
| ST segment elevation | 2.80 (1.04 to 7.52) | 3.53 (1.31 to 9.51) | 2.97 (1.09 to 8.12) | 2.63 (0.95 to 7.24) |
| Other | ||||
| LVH | 2.80 (1.44 to 5.46) | 1.89 (0.97 to 3.71) | 1.84 (0.93 to 3.62) | 2.06 (1.04 to 4.08) |
| Short PR interval | 0.34 (0.05 to 2.45) | 0.43 (0.06 to 3.09) | 0.42 (0.06 to 2.99) | 0.39 (0.05 to 2.81) |
| Major QT prolongation | 2.06 (1.34 to 3.16) | 1.62 (1.05 to 2.50) | 1.52 (0.98 to 2.37) | 1.40 (0.89 to 2.20) |
| Minor QT prolongation | 1.60 (1.05 to 2.44) | 1.59 (1.04 to 2.42) | 1.47 (0.96 to 2.26) | 1.46 (0.95 to 2.24) |
| Low QRS amplitude | 2.14 (1.01 to 4.16) | 1.80 (0.92 to 3.51) | 1.77 (0.87 to 3.64) | 1.86 (0.90 to 3.81) |
Figures in bold represent significant values. BNP indicates B‐type natriuretic peptide; LAH, left anterior hemiblock; LBBB, left bundle branch block; LVH, left ventricular hypertrophy; major QT prolongation, QTi>115%; MI, myocardial infarction; minor QT prolongation, QTi>111%; QTi, QT prolongation index: (QT/656)×(HR+100); RBBB, right bundle branch block; SPB, supraventricular premature beats; VBP, ventricular premature beats.
Adjusted for age, gender, diabetes mellitus, current smoking, systolic blood pressure, treatment for hypertension, ratio of total cholesterol to high‐density lipoprotein cholesterol and serum creatinine.
Adjusted for variables in * and BNP levels.