Table 6.
Prognostic Value of ECG Findings in Chagas Disease and Non‐Chagas Disease Elderly Patients According to the Classification of Severity and Number of Major ECG Abnormalities for Mortality, The Bambuí Cohort Study, 1997–2007
| ECG | HR (95% CI) | |||
|---|---|---|---|---|
| Unadjusted | Adjusted for Age and Gender | Adjusted for Clinical Variables* | Fully Adjusted Model* | |
| Classified according to severity | ||||
| Chagas disease (n=557) | ||||
| Normal ECG | 1 | 1 | 1 | 1 |
| Minor abnormality | 1.22 (0.72 to 2.05) | 1.19 (0.70 to 2.02) | 1.15 (0.67 to 1.95) | 1.10 (0.65 to 1.87) |
| Major abnormality | 2.93 (1.82 to 4.70) | 2.50 (1.55 to 4.03) | 2.31 (1.43 to 3.74) | 2.18 (1.35 to 3.53) |
| Non‐Chagas disease (n=905) | ||||
| Normal ECG | 1 | 1 | 1 | 1 |
| Minor abnormality | 1.09 (0.79 to 1.51) | 1.08 (0.78 to 1.49) | 1.04 (0.74 to 1.44) | 1.01 (0.72 to 1.41) |
| Major abnormality | 2.17 (1.59 to 2.97) | 1.77 (1.29 to 2.44) | 1.56 (1.12 to 2.18) | 1.50 (1.07 to 2.10) |
| Classified by the number of major abnormalities | ||||
| T. cruzi infected (n=557) | ||||
| 0 | 1 | 1 | 1 | 1 |
| 1 | 1.98 (1.44 to 2.71) | 1.67 (1.22 to 2.30) | 1.56 (1.13 to 2.16) | 1.53 (1.11 to 2.12) |
| 2 or more | 3.39 (2.49 to 4.60) | 3.01 (2.21 to 4.09) | 2.88 (2.11 to 3.93) | 2.78 (2.03 to 3.79) |
| Non Trypanosoma cruzi infected (n=905) | ||||
| 0 | 1 | 1 | 1 | 1 |
| 1 | 1.77 (1.37 to 2.28) | 1.56 (1.21 to 2.02) | 1.43 (1.09 to 1.86) | 1.37 (1.04 to 1.80) |
| 2 or more | 3.08 (2.21 to 4.30) | 2.05 (1.45 to 2.89) | 1.83 (1.28 to 2.62) | 1.83 (1.28 to 2.63) |
Figures in bold represent significant values. BNP indicates B‐type natriuretic peptide.
*
Adjusted for age, gender, diabetes mellitus, current smoking, systolic blood pressure, treatment for hypertension, ratio of total cholesterol to high‐density lipoprotein cholesterol and serum creatinine.
*
Adjusted for variables in * and BNP levels.