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. 2014 Feb 28;3(1):e000473. doi: 10.1161/JAHA.113.000473

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© 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 3. — SPECT myocardial perfusion imaging for the assessment of at‐risk myocardium. Diagram depicting conventional technetium‐based SPECT myocardial perfusion imaging with ^99mTc‐sestamibi/tetrofosmin for the assessment of myocardial salvage in 2 different hypothetical examples of acute ischemic myocardial injury in the left anterior descending (LAD) coronary artery territory. This technique requires 2 separate examinations with injection of radiotracer and imaging both before and after reperfusion. A, Pre‐reperfusion SPECT imaging reveals an area of decreased counts in the anteroseptum and anterior wall, whereas post‐reperfusion SPECT imaging shows normal myocardial perfusion. These findings suggest significant myocardial salvage in the left anterior descending coronary artery territory. B, Both pre‐reperfusion and postreperfusion SPECT images demonstrate decreased counts in the anteroseptum and anterior wall, suggesting no myocardial salvage in the left anterior descending coronary artery territory. ^99mTc indicates technetium‐99m; MI, myocardial infarction; SPECT, single‐photon emission computed tomography.