Table I.
Various antagonists that did not affect IL-12 levels following stress
| Exp. # | Stress type | Control groups | Stress groups | ||
|---|---|---|---|---|---|
| 4a | Wet-cage | vehicle 414 ± 28 |
propranolol 368 ± 21 |
vehicle* 307 ± 20 |
propranolol 290 ± 32 |
| 4b | Wet-cage | vehicle 355 ± 24 |
doxazosin 313 ± 18 |
vehicle* 257 ± 13 |
doxazosin 194 ± 17 |
| 4c | Wet-cage | vehicle 441 ± 17 |
naltrexone 409 ± 13 |
vehicle* 199 ± 12 |
naltrexone 205 ± 9 |
| 4d | Surgery | vehicle 487 ± 28 |
nadolol 474 ± 29 |
vehicle* 350 ± 52 |
nadolol 335 ± 47 |
Plasma IL-12 levels were assessed at 12 hrs following stress initiation and are presented as mean ± SEM.
*
indicates a significant reduction by exposure to stress paradigm