Table 1.

Pros and cons of implementing a diagnostic research protocol based on Alzheimer’s biomarker assessment in MCI patients.

Cons	Pros
–Experimental nature of biomarker assessment	–Robust scientific evidence has demonstrated the diagnostic value of biomarkers
–Pre-disability stage of the disorder and predictive nature of the diagnosis
–Lack of effective prevention and treatment options	–Respect for the patient’s wish to know what is going on in his/her brain
–Concern about “catastrophic reactions”	–Ability to plan for the future
–Risk of stigmatization and misuse of diagnostic results by third parties