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. 2014 Mar 19;6(2):e00140. doi: 10.1042/AN20140006

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© 2014 The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Licence (CC-BY)(http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC-BY) (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

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(A) Representative traces of population spikes in the presence of 50 μM AP5. AP5 reduced Roscovitine-LTP induction. (B) Representative traces of population spikes in the presence of 20 μM Roscovitine+10 μM Nifedipine. Nifedipine blocked Roscovitine-LTP induction. (C) Temporal course of population spikes in the presence of Roscovitine, Roscovitine+AP5 and Roscovitine+Nifedipine. (D) Box plot shows that population spikes amplitude increase triggered by Roscovitine was reduced significantly in the presence of AP5 or Nifedipine. (E–G) PPR in the presence of Rosco vitine+AP5, Roscovitine+Nifedipine is shown. (H) PPR analysis of the experimental conditions. *P<0.001.