Figure 3.

CD4⁺ T cell and CD11c⁺ DC dominant inflammatory cell phenotype in OVA-challenged mice. (A) Upper panel shows a prominent, largely perivascular and perifollicular influx of CD4⁺ T cells. Lower panel shows a dramatic accumulation of CD11c⁺ DCs. (B) The CD11c⁺ population was CD103⁻ and langerin negative. Rare double-positive cells presumably represent the minority steady-state DC subpopulation. (C) The majority of the inflammatory CD11c⁺ cells co-expressed CD11b, CD206, CD86, and CD36.

Abbreviations: CD, cluster of differentiation; DC, dendritic cell; OVA, ovalbumin.