Table 1.

Summary of variants in AI-23 candidate disease regions and variants discovered by exome sequencing

Region	Size (Mb)	Variants not in dbSNP 129 or MAF ≤ 1%	… and predicted functional	… and segregates with the disease
Chr2:154,600,940–173,240,770	18.64	31	3	1
Chr7:154,812,233–157,683,557	2.87	4	0	–
Chr10:80,853,408–90,425,474	9.57	8	0	–
Chr11:100,244,686–113,840,625	13.60	21	1	0
Chr12:4,023,387–21,726,294	17.70	41	0	–
Chr22:22,798,234–33,658,203	10.86	33	0	–
Total	72.6	138	4	1

The total variants identified in each region are shown.