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. Author manuscript; available in PMC: 2014 Mar 19.
Published in final edited form as: Biochem Biophys Res Commun. 2009 Jan 25;380(3):454–459. doi: 10.1016/j.bbrc.2009.01.083

Table 1.

Inhibition of P. falciparum growth by PfSPP inhibitors as measured by [3H]- hypoxanthine incorporation assay.

Parasite strain IC50 ± SE (μM)
(Z-LL)2-ketone L-685,458 DAPT
Dd2 1.08 ± 0.07 0.18 ± 0.03 >10
7G8 1.12 ± 0.05 0.21 ± 0.04 >10
FCR3 1.23 ± 0.04 0.23 ± 0.03 >10
HB3 1.06 ± 0.05 0.19 ± 0.02 >10

Each assay was repeated at least two times. The IC50values are means ± standard errors (SE) of the mean for experiments run in triplicate.