Table 3.
Modes of variation with % variance explained and associations with incident rHOA in men and women
| OVERALL (n=382 hips) | MEN ONLY (n=148 hips) | WOMEN ONLY (n=234 hips) | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Mode | % Variance Explained | Mode score1 ↑ or ↓ |
RHOA cases (n=190) OR2 (95% CI) | Mode score1 ↑ or ↓ |
Male RHOA cases OR2 (95% CI) | Mode score1 ↑ or ↓ |
Female RHOA cases OR2 (95% CI) |
| 1 | 37.4 | ↓ | 1.15 (0.90, 1.47) | ↓ | 1.66 (1.11, 2.48) | ↓ | 1.03 (0.67, 1.57) |
| 2 | 16.0 | ↑ | 1.02 (0.82, 1.28) | ↑ | 1.49 (1.01, 2.19) | ↓ | 1.21 (0.90, 1.63) |
| 3 | 12.5 | ↓ | 1.03 (0.83, 1.28) | ↑ | 1.30 (0.83, 2.05) | ↓ | 1.21 (0.91, 1.60) |
| 4 | 9.9 | ↓ | 1.12 (0.88, 1.43) | ↑ | 1.00 (0.68, 1.47) | ↓ | 1.11 (0.71, 1.71) |
| 5 | 5.1 | ↑ | 1.03 (0.82, 1.29) | ↓ | 1.10 (0.74, 1.64) | ↑ | 1.07 (0.78, 1.46) |
| 6 | 3.4 | ↓ | 1.18 (0.93, 1.49) | ↓ | 1.22 (0.82, 1.82) | ↓ | 1.07 (0.73, 1.55) |
| 7 | 2.6 | ↓ | 1.04 (0.83, 1.30) | ↑ | 1.07 (0.74, 1.55) | ↓ | 1.13 (0.82, 1.57) |
| 8 | 2.3 | ↑ | 1.00 (0.81, 1.24) | ↑ | 1.00 (0.68, 1.49) | ↑ | 1.18 (0.88, 1.57) |
| 9 | 1.7 | ↑ | 1.10 (0.88, 1.38) | ↓ | 1.13 (0.79, 1.61) | ↑ | 1.28 (0.94, 1.75) |
| 10 | 1.3 | ↑ | 1.01 (0.82, 1.25) | ↓ | 1.25 (0.89, 1.74) | ↑ | 1.15 (0.83, 1.61) |
| 11 | 1.1 | ↑ | 1.17 (0.93, 1.48) | ↑ | 1.17 (0.80, 1.72) | ↓ | 1.10 (0.78, 1.54) |
| 12 | 0.9 | ↓ | 1.12 (0.91, 1.39) | ↑ | 1.06 (0.76, 1.49) | ↓ | 1.30 (0.95, 1.78) |
| 13 | 0.7 | ↑ | 1.01 (0.82, 1.24) | ↓ | 1.05 (0.69, 1.58) | ↑ | 1.08 (0.82, 1.42) |
| 14 | 0.6 | ↑ | 1.08 (0.87, 1.34) | ↑ | 1.00 (0.70, 1.43) | ↑ | 1.21 (0.87, 1.67) |
1
Association with increase (↑) or decrease (↓) in mode score (e.g. for mode 1, the odds of rHOA are 15% higher for every one SD decrease in mode 1 score overall; among men, the odds of rHOA are 66% higher for every one SD decrease in mode 1 score).
2
Adjusted for sex, race, age, BMI, baseline KL grade