Table 1.
Characteristic | Varenicline + Bupropion SR (n = 249) |
Varenicline + Placebo (n = 257) |
---|---|---|
Age, years, mean±SD | 42.2±12.2 | 41.9±12.7 |
Gender, n (%) | ||
Female | 113 (45) | 126 (49) |
Male | 136 (55) | 131 (51) |
Race, n (%) | ||
White, non-Hispanic | 234 (94) | 240 (93) |
Other | 15 (6) | 17 (7) |
Marital status, n (%)a | ||
Never married | 73 (29) | 69 (27) |
Separated/divorced | 53 (21) | 70 (27) |
Married/living as married | 112 (45) | 111 (43) |
Widowed/other | 10 (4) | 7 (3) |
Highest level of education, n (%)a | ||
High school graduate or less | 54 (22) | 67 (26) |
Some college | 156 (63) | 137 (53) |
College graduate or higher | 38 (15) | 53 (21) |
Current smoking rate, cigarettes per day, mean±SD | 19.5±7.3 | 19.7±7.9 |
< 20 cpd, n (%) | 102 (41) | 105 (41) |
≥ 20 cpd, n (%) | 147 (59) | 152 (59) |
Fagerström Test for Nicotine Dependence, mean±SDb | 5.2±2.0 | 5.3±2.0 |
≤ 5, n (%) | 127 (51) | 133 (52) |
≥ 6, n (%) | 120 (49) | 123 (48) |
Duration of regular smoking, years, mean±SDa | 23.5±12.1 | 23.3±12.0 |
Age when started smoking, years, mean±SDa | 17.6±3.9 | 17.5±4.1 |
Ever made serious attempt to quit? n (%)a | ||
No | 28 (11) | 19 (7) |
Yes | 220 (89) | 238 (93) |
Other tobacco users in household, n (%)a | ||
No | 155 (63) | 162 (63) |
Yes | 93 (37) | 95 (37) |
Abbreviations: SR, sustained-release, SD, standard deviation.
Missing data for 1 participant in the varenicline + bupropion SR group.
Scores range from 0 to 10 with higher scores indicating greater levels of nicotine dependence. An FTND score ≤ 5 indicates a low/moderate level of dependence and an FTND score of ≥ 6 indicates a high level of dependence. Missing data for 1 participant in the varenicline + placebo group and 2 participants in the varenicline + bupropion group.