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Competitive binding experiment measuring the displacement of 4 from PAN. (▼) DMSO negative control (0% inhibition) (◊) 250 μM compound 2 (100% inhibition) (●) Compound 2 (Ki = 0.09 μM) (■) DPBA (Ki = 0.48 μM) (▲) Compound 3 (Ki = 0.85 μM) (♦) Compound 19 (no inhibition).
