Figure 5. CHYS inhibits activation of Smad signaling in the diabetic kidney.
Phosphorylated Smad2/3 (p-Smad2/3) nuclear location (A. Magnification×400). Quantitative analysis of nucleated p-Smad2/3 in glomeruli (B) and tubulointerstitium (C) respectively. Data represent mean ± SE for groups of 14 rats. *P<0.05, **P<0.01, ***P<0.001 vs. sham group; # P<0.05, ## P<0.01, ### P<0.001 vs. DN group.
