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. 2014 Mar 19;9(3):e91065. doi: 10.1371/journal.pone.0091065

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© 2014 Muller et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Average motor threshold per treatment group. Percent machine output needed to achieve motor thresholds across sham 1(74.2%MO ±7.3%MO, 75.8%MO ±4.9%MO, 74.2%MO ±3.8%MO, 70%MO ±4.5%MO respectively). No significant difference between groups was detected. Error bars indicate SD. (B) Effects of NMDAR antagonists on MEP suppression by 1 Hz rTMS. Integrated MEP voltage (uV*s) is measured at 80% MO. Statistics per treatment pair were obtained by comparison with the corresponding sham condition. For the 1 Hz rTMS group, there is a 48.2% (p<0.01) and 53% (p<0.05) reduction at the 8-minutes and 35-minutes timepoints after rTMS, respectively. There is no significant change from pre-rTMS baseline after pretreatment with MK801 or AP5 conditions. Error bars indicate SD.*p<0.05, **p<0.01.