Table 3. Superposition Analysis of ChxREff with OmpR/PhoB Subfamily Effector Domains.
OmpR/PhoB Effector Domain | Corresponding Cα Positionsa | RMSD (Å) | Sequence Identity (%) | LGA_Sb |
OmpR | 88/104 | 2.49 | 25.0 | 51.2 |
PhoB | 83/104 | 2.36 | 28.9 | 53.6 |
PhoP | 78/98 | 2.38 | 25.6 | 47.1 |
KdpE | 86/101 | 2.37 | 25.6 | 49.0 |
HP1043 | 82/106 | 2.38 | 22.0 | 47.8 |
Denotes the number of Effector Domain residues that superimpose within 5.0 Å distance of an equivalent position in ChxREff.
The LGA_S parameter represents a scoring function to evaluate the overall levels of structural similarity between two sets of coordinates. For each set of corresponding residues, it combines information pertaining to both the fraction of residues that overlap within a given RMSD window as well as those that overlap within a given distance cutoff (5.0 Å) [37].