Table 6. Significant cytokines at different phases of illness when compared to the controls.
Cytokines | Controls | Febrile | Defervescence | Convalescence |
Inflammatory cytokines | ||||
IL-5 | 2.63±0.90 | – | – | DwWS ↑↑ (9.34±1.07) |
IL-10 | 11.32±1.89 | DwWS ↓↓ (0.03±0.01) | DwWS ↓↓ (0.02±0.01) | DwoWS ↓↓ (0.01±0.00) |
IL-13 | 8.42±1.90 | – | – | DwWS ↑↑ (31.61±3.41) |
IFN-γ | 157.20±32.98 | – | – | DwWS ↑↑ (408.60±24.87) |
MIF | 267.19±53.76 | DwWS ↑↑ (2497.00±341.90) | DwWS ↑↑ (2201.00±354.50) | DwWS ↑↑ (5166.00±3444.00) |
Chemokines | ||||
IL-8 | 64.28±11.27 | DwWS ↓↓ (37.06±9.47) | DwWS ↓↓ (27.21±2.14) | – |
CCL11 | 184.40±16.32 | DwWS ↓↓ (126.90±29.12) | DwWS ↓↓ (101.80±13.22) | – |
CXCL10 | 1115.00±250.50 | DwWS ↑↑ (172084.00±90626.00) | DwoWS ↑↑ (115716.00±87093.00) | – |
DwWS ↑↑ (41443.00±10265.00) | ||||
Adhesion molecules | ||||
ICAM-1 | 79313.00±5389. 00 | – | DwWS ↑↑ (228076.00±25693.00) | – |
VCAM-1 | 203603.00±23245.11 | DwWS ↑↑ (460438.0±39075.0) | DwoWS ↑↑(430763.0±48866.0) | – |
DwWS ↑↑(461180.0±46475.0) | ||||
Growth factors | ||||
IL-7 | 8.59±1.93 | DwWS ↑↑ (130.10±14.37) | DwWS ↑↑ (142.90±20.93) | DwWS ↑↑ (242.20±24.80) |
FGF-2 | 114.00±28.240 | DwWS ↓↓ (45.83±4.72) | – | – |