Figure 1. Cdk5 contributes to neuroendocrine thyroid cancer tumorigenesis.

A, a schematic model showing the proposed mechanism by which Cdk5 mediates MTC proliferation; B, a scanning electron micrograph of cultured mouse thyroid C cells that were derived from a mouse MTC; the cells grow in suspension, as floating clusters. Assistance for SEM was provided by Anza Darehshouri and Robyn Leidel of the UT Southwestern Electron Microscopy Core Facility for assistance with the Zeiss Sigma VP SEM, on loan to UTSW from Carl Zeiss Microscopy.