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. 2014 Mar 19;9(3):e92326. doi: 10.1371/journal.pone.0092326

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© 2014 Zhang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Immunohistochemical staining with anti-CD31 antibody. The arrow indicates a representative microvessel within the tumor (magnification, 400×). (B) MVD was determined by identifying the three most intense areas of neovascularization of each sample and counting at low power (magnification, 100×). Average vessel counts of the three selected fields were recorded.*P<0.05.