Table 1. Baseline characteristics of patient cohorts as described in figure 1.
| Cohort A | ||||||
| INS | No INS | p-value | NDAF | No NDAF | p-value | |
| number of patients, n | 18 | 86 | 13 | 91 | ||
| age [y], median (IQR) | 72 (57 – 77) | 68 (59 – 79) | 0.98 | 71 (67 – 81) | 68 (59 – 77) | 0.13 |
| NIHSS [pts], median (IQR) | 11 (4 – 15) | 4 (2 – 7) | 0.0019* | 5 (2 – 16.5) | 4 (2 – 8) | 0.28 |
| female sex, % (n) | 56 (10) | 38 (33) | 0.18 | 38 (5) | 42 (38) | 0.82 |
| systolic blood pressure [mmHg], median (IQR) | 144 (130 – 170) | 168 (140 – 183) | 0.10 | 164 (141 – 184) | 166 (141 – 185) | 0.88 |
| heart rate, median [min−1] (IQR) | 73 (64 – 89) | 68 (75 – 89) | 0.66 | 64 (71 – 78) | 76 (67 – 90) | 0.31 |
| history of coronary artery disease, % (n) | 17 (3) | 21 (18) | 0.68 | 15 (2) | 21 (19) | 0.64 |
| history of arterial hypertension, % (n) | 78 (14) | 79 (68) | 0.78 | 77 (10) | 74 (67) | 0.80 |
| lesion size on DWI [mL], median (IQR) | 45.3 (9.8 – 100.5) | 0.9 (0.1 – 4.1) | < 0.0001* | 16.4 (2.8 – 91.1) | 1.2 (0.1 – 6.6) | 0.0012* |
| MR-proANP on admission [pM], median (IQR) | 151.0 (102.1 – 255.8) | 98.5 (68.7 – 169.0) | 0.04* | 207.0 (122.5 – 341.0) | 98.1 (67.5 – 161.3) | 0.0004* |
| Involvement of the insular cortex, % (n) | n/a | n/a | 38 (5) | 14 (13) | 0.03* | |
| Newly-diagnosed atrial fibrillation, % (n) | 28 (5) | 9 (8) | 0.03* | n/a | n/a | |
(INS = insular stroke, NDAF = newly diagnosed atrial fibrillation, NIHSS = National Institute of Health Stroke Scale, IQR = Interquartile Range, CAD = coronary artery disease).*p<0.05.