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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Free Radic Biol Med. 2014 Jan 14;69:1–14. doi: 10.1016/j.freeradbiomed.2014.01.004

Figure 7.

Figure 7

The UPR is induced and mitochondria are injured in the RPE/choroid 24 hours after mice were given an intravitreal injection of CSE. A. Western blot of IRE1α after mice received intravitreal injection of 250ug/ml CSE in one eye and vehicle in the other eye. B. Graph showing increased IRE1α protein in the RPE/choroid after intravitreal injection of 250ug/ml CSE compared to vehicle control. *p<0.05; n=3 eyes per condition. C. Graph showing decreased ATP production in the RPE/choroid of eyes that received an intravitreal injection of 250ug/ml CSE compared to vehicle control. *p<0.05; n=6 eyes per condition.