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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Free Radic Biol Med. 2014 Jan 14;69:1–14. doi: 10.1016/j.freeradbiomed.2014.01.004

Table 3A.

IRE 1 alpha Immunolabeling of the RPE in early AMD

Donor Age (Yrs) Gender Race D–E (Hr) RPE Macula Periphery
BrM Small Drusen Large Drusen BrM Small Drusen Large Drusen
Unaffected
1 65 M B 22 Yes NP NP Yes NP NP
2 62 F B 40 Yes NP NP Yes NP NP
3 52 M W 23 Yes NP NP Yes NP NP
4 42 F W 14 Yes NP NP Yes NP NP
5 54 M W 13 Yes NP NP Yes NP NP
6 83 F W 13 Yes NP NP Yes NP NP
Early AMD
1 60 M B 28 Yes Yes No Yes NP NP
2 96 F W 19 Yes NP No Yes NP NP
3 61 M W 20 Yes Yes No Yes NP NP
4 87 F W 24 Yes Yes No Yes NP NP
5 83 F W 12 Yes NP No Yes NP NP
6 94 F W 8 Yes NP No Yes NP NP
7 68 F W 20 Yes Yes No Yes NP NP

IRE1a immunolabeling in the RPE overlying unthickened Bruch’s membrane (BrM) or when overlying small or hard drusen. D–E, death to enucleation; F, female; M, male; B, Black; W, White; NP, not present.