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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Free Radic Biol Med. 2014 Jan 14;69:1–14. doi: 10.1016/j.freeradbiomed.2014.01.004

Table 3B.

TOM 20Immunolabeling of the RPE in early AMD

Donor Age (Yrs) Gender Race D–E (Hr) RPE Macula Periphery
BrM Small Drusen Large Drusen BrM Small Drusen Large Drusen
Unaffected
1 65 M B 22 Yes NP NP Yes NP NP
2 62 F B 40 Yes NP NP Yes NP NP
3 52 M W 23 Yes NP NP Yes NP NP
4 42 F W 14 Yes NP NP Yes NP NP
5 54 M W 13 Yes NP NP Yes NP NP
6 83 F W 13 yes NP NP Yes NP NP
Early AMD
1 60 M B 28 Yes Yes* No Yes NP NP
2 96 F W 19 Yes NP No Yes NP NP
3 61 M W 20 Yes No No Yes NP NP
4 87 M W 24 Yes No No Yes NP NP
5 83 F W 12 Yes NP No Yes NP NP
6 94 F W 8 Yes NP No Yes NP NP
7 68 F W 20 Yes Yes* No Yes NP NP

TOM20 immunolabeling in the RPE overlying unthickened Bruch’s membrane (BrM) or when overlying small or hard drusen. D–E, death to enucleation; F, female; M, male; B, Black; W, White; NP, not present. Yes* indicates decreased immunolabeling compared to adjacent RPE.