. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: J Allergy Clin Immunol. 2013 Oct 17;133(2):357–362.e8. doi: 10.1016/j.jaci.2013.09.003

TABLE III.

Analysis of prematurity requiring NICU admission and asthma in participating children after stratification by atopy (≥1 positive allergen-specific IgE)^*^†

Covariate	OR (95% CI)
Covariate	Nonatopic children (n = 239)	Atopic children (n = 353)
Unadjusted
Prematurity requiring NICU admission	1.1 (0.2–5.1), P = .9	5.0 (1.1–22.4), P = .03
Adjusted^‡^§
Prematurity requiring NICU admission	0.4 (0.1–3.0), P = .4	6.3 (1.4–28.9), P = .02
Maternal history of asthma	4.7 (2.5–8.7), P < .001	3.6 (2.2–5.9), P < .001
Exposure to ETS in utero or before age 2 y	1.6 (0.9–3.0), P = .1	1.5 (0.9–2.4), P = .1

Allergen-specific IgE levels were available for 592 (287 control subjects and 305 cases) of the 678 participating children.

^†

Asthma was defined as physician-diagnosed asthma and wheeze in the previous year.

^‡

Multivariate logistic regression models were adjusted for age, sex, and household income in addition to the covariates listed in the first column.

^§

Goodness of fit for each of the multivariate models was assessed by using the Hosmer-Lemeshow test (P =.9 for the model in nonatopic children and P =.8 for the model in atopic children).