Table 2.
Q1 | Q2 | Q3 | Q4 | p-trend | |
---|---|---|---|---|---|
DBP a | |||||
# cases/# controls | 98 / 58 | 62 / 76 | 71 / 53 | 29 / 73 | |
ORb (95% CI) | 1.0 (ref) | 0.42 (0.25 – 0.71) | 0.80 (0.48 – 1.33) | 0.17 (0.09 – 0.32) | <0.0001 |
ORc (95% CI) | 1.0 (ref) | 0.41 (0.25 – 0.70) | 0.76 (0.45 – 1.28) | 0.17 (0.09 – 0.33) | <0.0001 |
ORd (95% CI) | 1.0 (ref) | 0.40 (0.24 – 0.68) | 0.75 (0.44 – 1.28) | 0.17 (0.08 – 0.33) | <0.0001 |
| |||||
25(OH)D e | |||||
# cases/# controls | 68 / 73 | 64 / 67 | 74 / 74 | 75 / 67 | |
ORb (95% CI) | 1.0 (ref) | 1.03 (0.66 – 1.60) | 1.07 (0.69 – 1.67) | 1.20 (0.76 – 1.90) | 0.62 |
ORc (95% CI) | 1.0 (ref) | 1.07 (0.68 – 1.70) | 1.07 (0.68 – 1.68) | 1.28 (0.79 – 2.05) | 0.50 |
ORd (95% CI) | 1.0 (ref) | 0.99 (0.60 – 1.63) | 1.17 (0.71 – 0.91) | 1.45 (0.86 – 2.44) | 0.18 |
| |||||
25(OH)D:DBP Molar Ratio (×103) | |||||
Range | < 3.9 | 3.9 – <5.9 | 5.9 – <9.0 | ≥ 9.0 | |
# cases/# controls | 60 / 70 | 66 / 65 | 61 / 68 | 73 / 57 | |
ORb (95% CI) | 1.0 (ref) | 1.18 (0.73 – 1.92) | 1.03 (0.64 – 1.66) | 1.57 (0.94 – 2.62) | 0.12 |
ORc (95% CI) | 1.0 (ref) | 1.11 (0.67 – 1.85) | 1.04 (0.63 – 1.72) | 1.61 (0.95 – 2.73) | 0.09 |
February 2011 outpoints (in nmol/L) = Q1: <4,396, Q2: 4,396 – <5,569, Q3: 5,569 – < 6,999, Q4: ≥ 6,999; December 2011 outpoints (in nmol/L) = Q1: <4,896, Q2: 4,896 – <6,155, Q3: 6,155 – <7,637, Q4: ≥ 7,637
Conditioned on age and date of baseline blood collection.
Conditioned on age and date of baseline blood collection and adjusted for hypertension, BMI, and cigarettes smoked per day.
Conditioned on age and date of baseline blood collection and adjusted for hypertension, BMI, and cigarettes smoked per day. Models are mutually adjusted for DBP and 25(OH)D.
Winter quartile outpoints (in nmol/L) = Q1: <19, Q2: 19 – <29, Q3: 29 – <44, Q4: ≥44; summer quartile outpoints (in nmol/L) = Q1: <29, Q2: 29 – <43, Q3: 43 – <57, Q4: ≥57