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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Int J Cancer. 2014 Jan 30;134(11):2699–2706. doi: 10.1002/ijc.28596

Table 2.

Odds ratios and 95% confidence intervals for the association between serum DBP, serum 25(OH)D, and 25(OH)D:DBP molar ratio, and renal cell carcinoma risk

Q1 Q2 Q3 Q4 p-trend
DBP a
# cases/# controls 98 / 58 62 / 76 71 / 53 29 / 73
ORb (95% CI) 1.0 (ref) 0.42 (0.25 – 0.71) 0.80 (0.48 – 1.33) 0.17 (0.09 – 0.32) <0.0001
ORc (95% CI) 1.0 (ref) 0.41 (0.25 – 0.70) 0.76 (0.45 – 1.28) 0.17 (0.09 – 0.33) <0.0001
ORd (95% CI) 1.0 (ref) 0.40 (0.24 – 0.68) 0.75 (0.44 – 1.28) 0.17 (0.08 – 0.33) <0.0001
25(OH)D e
# cases/# controls 68 / 73 64 / 67 74 / 74 75 / 67
ORb (95% CI) 1.0 (ref) 1.03 (0.66 – 1.60) 1.07 (0.69 – 1.67) 1.20 (0.76 – 1.90) 0.62
ORc (95% CI) 1.0 (ref) 1.07 (0.68 – 1.70) 1.07 (0.68 – 1.68) 1.28 (0.79 – 2.05) 0.50
ORd (95% CI) 1.0 (ref) 0.99 (0.60 – 1.63) 1.17 (0.71 – 0.91) 1.45 (0.86 – 2.44) 0.18
25(OH)D:DBP Molar Ratio (×103)
Range < 3.9 3.9 – <5.9 5.9 – <9.0 ≥ 9.0
# cases/# controls 60 / 70 66 / 65 61 / 68 73 / 57
ORb (95% CI) 1.0 (ref) 1.18 (0.73 – 1.92) 1.03 (0.64 – 1.66) 1.57 (0.94 – 2.62) 0.12
ORc (95% CI) 1.0 (ref) 1.11 (0.67 – 1.85) 1.04 (0.63 – 1.72) 1.61 (0.95 – 2.73) 0.09
a

February 2011 outpoints (in nmol/L) = Q1: <4,396, Q2: 4,396 – <5,569, Q3: 5,569 – < 6,999, Q4: ≥ 6,999; December 2011 outpoints (in nmol/L) = Q1: <4,896, Q2: 4,896 – <6,155, Q3: 6,155 – <7,637, Q4: ≥ 7,637

b

Conditioned on age and date of baseline blood collection.

c

Conditioned on age and date of baseline blood collection and adjusted for hypertension, BMI, and cigarettes smoked per day.

d

Conditioned on age and date of baseline blood collection and adjusted for hypertension, BMI, and cigarettes smoked per day. Models are mutually adjusted for DBP and 25(OH)D.

e

Winter quartile outpoints (in nmol/L) = Q1: <19, Q2: 19 – <29, Q3: 29 – <44, Q4: ≥44; summer quartile outpoints (in nmol/L) = Q1: <29, Q2: 29 – <43, Q3: 43 – <57, Q4: ≥57