. Author manuscript; available in PMC: 2015 Nov 1.

Published in final edited form as: Am J Geriatr Psychiatry. 2013 Jul 24;22(11):1168–1179. doi: 10.1016/j.jagp.2013.03.006

Table 3.

Longitudinal mixed effects model of association of baseline bilateral averaged regional cortical thickness and apathy over time, displaying predictors retained in the final model.

Model: Correlations of predicted values versus actual values of the dependent variable: Pearson r=0.44, r²=0.20, df=2823, p<0.0001 for fixed effects; r=0.77, r ²=0.59, df=2821, p<0.0001 including random terms.
Predictor		β	95% CI for β	F	df	p
Inferior temporal		0.30	0.11, 0.49	9.4	1,1341	0.002
Time in study (years)		0.64	0.35, 0.93	18.9	1,720	<0.0001
Inferior temporal x time		−0.22	−0.33, −0.11	15.4	1,1341	<0.0001
Baseline Apathy		0.35	0.29, 0.41	152.5	1,1341	<0.0001
Antidepressant medication use	Yes	0.08	0.004, 0.15	4.3	1,761	0.04
Antidepressant medication use	No	0	0.004, 0.15	4.3	1,761	0.04
Baseline AD dementia symptom duration (years)		0.04	0.02, 0.06	20.3	1,1341	<0.0001
Baseline RAVLT Total Encoding		−0.006	−0.009, −0.003	14.9	1,1341	0.0001
Baseline Digit Symbol		−0.005	−0.008, −0.003	15.5	1,1341	<0.0001

AD (Alzheimer’s disease), β (partial regression coefficient estimate), CI (confidence interval), df (degrees of freedom), F (F test statistic), RAVLT (Rey Auditory Verbal Learning Test). x indicates an interaction.