Figure 4.

M867 Inhibits Radiation Induced, Caspase-3 Mediated Lung Injury. A: One mouse from each treatment group was sacrificed. Mice lungs were removed and immunostained for active caspase-3. Shown are representative photographs of histology slides, magnification is x 40. B: Also shown is a bar graph of mean (10 random fields) percentages of cells that stained positive for active caspase-3 with SEM. P-values are indicated. C: Western blots detected cleaved caspase-3 in protein extracts of mice lungs. Actin was the loading control.